Award
NIH Reporter #1R21NS146792-01
Cholinergic regulation of epidermal neurons
Recipient
NIGEL A. CALCUTT
Award Amount
$439,875.00
Ceiling
$439,875.00
Awarded
June 12, 2026
Identifier
1R21NS146792-01
NIH grant awarded by NINDS for research on cholinergic regulation of epidermal neurons, focusing on acetylcholine's role in sensory neuron growth using mouse models. Award amount is $439,875 for a 2-year project.
Description
The project aims to test the hypothesis that keratinocyte-derived acetylcholine constrains sensory neuron growth via M1R. The project involves in vitro and in vivo studies using mouse models with conditional knockdown of choline acetyltransferase in keratinocytes. The funding agency is the National Institute of Neurological Disorders and Stroke (NINDS), part of NIH. The project is part of the PA-25-150 funding opportunity. The project duration is approximately 2 years.