Award
NIH Reporter #11395466
Synergistic Effect of Nicotine and Antiretrovirals on Placental Development
Recipient
University of Nebraska Medical Center
Award Amount
$711,164.00
Ceiling
$711,164.00
Awarded
June 08, 2026
Identifier
11395466
Research project funded by NIH to study the combined effects of nicotine and antiretroviral drugs on placental development and to develop protective drug delivery methods.
Description
The project focuses on the effects of co-exposure to INSTIs and nicotine on placental development. It aims to develop long-acting delivery formulations to mitigate adverse effects. The project involves assessment of trophoblast functions, placental development in rodent models, and evaluation of delivery methods, emphasizing understanding synergistic effects and protective delivery strategies.