Award
National Institute of Diabetes and Digestive and Kidney Diseases 1R01DK145533-01
Mechanisms of epithelial cell state changes during kidney injury
Recipient
University of Michigan at Ann Arbor, MI
Award Amount
$690,854.00
Ceiling
$690,854.00
Awarded
January 27, 2026
Identifier
1R01DK145533-01
This NIH-funded project investigates the role of the transcription factor Pax8 in kidney epithelial cell state changes during injury, aiming to develop new therapeutic strategies for kidney injury and related diseases.
Description
The project aims to identify molecular and genetic mechanisms that determine and maintain kidney epithelial cell states in normal physiology and in response to injury. It focuses on the role of the transcription factor Pax8 in kidney regeneration after injury, exploring its targets and functions to develop new treatments for kidney injury.