Award
National Institute of Biomedical Imaging and Bioengineering 5K99EB037080-02
Accurate High-Resolution Tissue Characterization for Breast Cancer Screening Using Transmission and Reflection Ultrasound Tomography
Recipient
University of Rochester
Award Amount
$124,904.00
Ceiling
$124,904.00
Awarded
August 03, 2026
Identifier
5K99EB037080-02
This award funds research to improve ultrasound tomography for breast cancer screening by enhancing imaging resolution and accuracy without radiation or compression, enabling early cancer detection and broader imaging applications.
Description
The proposed research aims to expand the capability and performance of ultrasound tomography as an imaging modality that enables greater sensitivity and specificity for breast cancer screening without using compression or ionizing radiation. The project will improve modeling and inversion techniques used in ultrasound tomography to better accommodate high-frequency signals, increasing imaging resolution and accuracy. It will also develop a prototype to capture 3D insonification of tissue, incorporate reflected signals into full-waveform inversion (FWI), and recover sharp boundaries caused by impedance changes. These advancements will enhance tissue characterization, enable early cancer detection, and broaden applications such as small-animal and transcranial imaging.