Award
National Institute of Arthritis and Musculoskeletal and Skin Diseases 3UC2AR082195-02S1
Comprehensive functional phenotyping of trigeminal neurons innervating temporomandibular joint (TMJ) tissues in male, female, and aged mice, primates, and humans with and without TMJ disorders (TMJD)
Recipient
University of Texas Health Science Center
Award Amount
$279,997.00
Ceiling
$279,997.00
Awarded
September 09, 2025
Identifier
3UC2AR082195-02S1
Research project to map and phenotype trigeminal neurons in TMJ tissues to understand TMJ disorders and develop new treatments.
Description
The project aims to elucidate the functions, types, neuroanatomical distributions, and plasticity of trigeminal neurons innervating TMJ tissues across mice, primates, and humans, with a focus on TMJ disorders. It involves mapping neuron phenotypes, plasticity, and identifying therapeutic targets.