# NIH Reporter #1R35GM161216-01

Defining Centriolar Plaque Architecture and Function Across Eukaryotic Diversity Using Expansion Microscopy and Proteomics

**Recipient:** Indiana University Indianapolis

**Award Amount:** $396,250.00
**Ceiling:** $396,250.00

**Awarded:** February 20, 2026

**Identifier:** 1R35GM161216-01

The award supports research at Indiana University Indianapolis to map centriolar plaque composition and function, examining conserved and taxon-specific features of eukaryotic cell division.

### Description

Research project using expansion microscopy, proteomics, functional analyses, and CRISPR-Cas9 technology to investigate centriolar plaque architecture and its roles in microtubule-organizing center formation, cell polarity, and organelle segregation during eukaryotic cell division.

[View original record](https://reporter.nih.gov/search/J7l2tQ4hHkqRePwGq3m5kA/project-details/11258119)