Award
National Heart, Lung, and Blood Institute 5U24HL173568-03
2/2 Data Coordinating Center for the Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure with Preserved Ejection Fraction Study (SPIRRIT-EX)
Recipient
Duke University
Award Amount
$538,632.00
Ceiling
$538,632.00
Awarded
June 01, 2026
Identifier
5U24HL173568-03
This award funds a 5-year clinical trial led by Duke University to evaluate spironolactone's effectiveness in treating heart failure with preserved ejection fraction, including follow-up and secondary analyses.
Description
The project involves a clinical trial to evaluate the effectiveness of spironolactone in heart failure with preserved ejection fraction (HFpEF). The trial is funded for 5 years, with follow-up extended through 2025. The project includes secondary analyses, dissemination, and closeout activities. The study aims to determine the efficacy of spironolactone in HFpEF patients.