Award
National Institute of Allergy and Infectious Diseases 5R01AI165510-04
Serine/threonine kinase signaling in beta-lactam resistance of Staphylococcus aureus
Recipient
University of Maryland Baltimore, Baltimore, MD
Award Amount
$669,744.00
Ceiling
$669,744.00
Awarded
July 28, 2026
Identifier
5R01AI165510-04
Research project funded by NIAID to investigate the role of eSTK signaling in broad-spectrum β-lactam resistance in MRSA, aiming to understand classical and non-classical resistance mechanisms.
Description
Study to decipher the mechanisms through which eukaryotic-like serine/threonine kinase (eSTK) controls mecA expression, identify mediators conferring non-classical resistance, and investigate compensatory resistance mechanisms in methicillin-resistant Staphylococcus aureus (MRSA).