Award
National Institute of General Medical Sciences 5R35GM124725-09
From intra to intercellular regulatory networks that define cell type identity
Recipient
Johns Hopkins University
Award Amount
$458,500.00
Ceiling
$458,500.00
Awarded
July 17, 2025
Identifier
5R35GM124725-09
A research grant awarded to Johns Hopkins University to develop computational tools and generate data for improving cell fate engineering, focusing on synovial joint development and single-cell analysis.
Description
This project focuses on improving the fidelity of cell fate engineering by developing computational tools to analyze single-cell omics data, infer regulatory networks, and generate reliable differentiation protocols. The work involves generating single-cell RNA sequencing data, adopting differentiation protocols, and creating platforms for assessing cell identity. The goal is to make cell fate engineering more reliable and controllable, shedding light on how signaling pathways and regulatory networks interact during development.