Award
National Institute of Allergy and Infectious Diseases 5R01AI158372-05
Remodeling of intracellular membrane traffic by Brucella effectors
Recipient
University of Vermont & St. College
Award Amount
$667,427.00
Ceiling
$667,427.00
Awarded
March 30, 2026
Identifier
5R01AI158372-05
The project investigates how Brucella bacteria use effector proteins to manipulate Golgi apparatus functions to support their intracellular survival and replication, advancing understanding of bacterial pathogenesis and host cell biology.
Description
This project aims to characterize how Brucella effector proteins modulate Golgi-associated membrane transport to promote bacterial proliferation, with implications for microbial pathogenesis and cell biology.