Award
National Institute of Diabetes and Digestive and Kidney Diseases 5R01DK113788-07
Exploring the role, regulation, and antimicrobial function of Paneth cell peptides PYY and NPY in maintaining gut microbial commensalism and innate immune defense
Recipient
University of Chicago
Award Amount
$686,715.00
Ceiling
$686,715.00
Awarded
February 16, 2026
Identifier
5R01DK113788-07
NIH grant awarded to University of Chicago to study antimicrobial peptides PYY and NPY in gut health and immune defense, funded by NIDDK.
Description
The project focuses on investigating antimicrobial peptides PYY and NPY in gut health using in vivo, in vitro, and ex vivo approaches, including genetically modified mice. It aims to understand the regulation and antimicrobial spectrum of peptides PYY and NPY.