Award
National Institute of Diabetes and Digestive and Kidney Diseases 7U01DK115575-05
Fecal Incontinence Treatment Study (FIT Study)
Recipient
Mayo Clinic Rochester
Award Amount
$1,377,218.00
Ceiling
$1,377,218.00
Awarded
August 30, 2023
Identifier
7U01DK115575-05
A research project funded by the National Institute of Diabetes and Digestive and Kidney Diseases to compare three treatments for fecal incontinence, assessing their efficacy, safety, cost, and predictors of treatment response over two years.
Description
This project is an initial application for a U01 (PAR 15-067) focusing on comparing three validated treatments for moderate to severe fecal incontinence: biofeedback, sacral nerve stimulation, and injection with the inert bulking agent dextranomer. The study involves randomizing patients to these treatments, assessing efficacy, safety, and cost, and following patients for two years. It aims to identify physiological, clinical, and psychosocial predictors of treatment response.