Award
NIH Reporter #11313526
Metabolic Plasticity and Neuronal Resilience: Unraveling Adaptive Responses to Chronic mtDNA Damage
Recipient
University of California, San Diego
Award Amount
$43,446.00
Ceiling
$43,446.00
Awarded
January 21, 2026
Identifier
11313526
Research project funded by the National Institute of Neurological Disorders and Stroke to study the effects of chronic mitochondrial DNA damage on neuronal energy metabolism and resilience.
Description
This project aims to investigate how chronic mitochondrial DNA damage affects energy metabolism in neurons, potentially leading to neurodegenerative diseases. The study involves models that modify mtDNA in mature neurons and aims to identify molecular pathways involved in neuronal decline and resilience.