Award
NIH Reporter #5R01AI174599-04
Optimization of Atypical Antimycobacterial Carbapenem Antibiotics
Recipient
National Institute of Allergy and Infectious Diseases (NIAID), part of the NIH
Award Amount
$673,531.00
Ceiling
$673,531.00
Awarded
July 07, 2026
Identifier
5R01AI174599-04
Award for research on developing new atypical carbapenem antibiotics targeting mycobacterial pathogens, funded by NIH/NIAID for $673,531.
Description
The project involves the design, synthesis, and evaluation of new antibiotics targeting mycobacterial pathogens, including Mycobacterium tuberculosis and nontuberculous mycobacteria. Focus on developing orally bioavailable antimycobacterial agents with improved specificity. The project includes the synthesis of atypical carbapenem antibiotics with structural modifications to enhance activity and stability. The award is funded by the NIH/NIAID with a total amount of $673,531 for fiscal year 2026. The project duration is from July 19, 2023, to June 30, 2028. The award notice date is July 7, 2026. The full funding opportunity is PA-20-185. The project is managed by a team including synthesis, microbiology, biochemistry, and structural biology experts.