Award
NIH Reporter #5R01HL175577-02
"Outside-in” Model of Cardiac Pacemaking: Extracellular Mediated Automaticity
Recipient
UNIV OF NORTH CAROLINA CHAPEL HILL
Award Amount
$680,708.00
Ceiling
$680,708.00
Awarded
May 20, 2026
Identifier
5R01HL175577-02
NIH funded project by UNIV OF NORTH CAROLINA CHAPEL HILL to study cardiac pacemaking through extracellular ionic fluctuations using computational and in vivo methods.
Description
The project aims to test a novel model of cardiac pacemaking focusing on extracellular ionic fluctuations. The project involves computational modeling and in vivo experimentation. It includes aims to define [K+]o as a critical ionic species and mechanisms controlling extracellular ion distribution.