Award
NIH Reporter #5R01ES037332-02
Prenatal Exposure to Organophosphate Ester Flame Retardants and Plasticizers (OPEs), Gene-Environment Interaction, and Child Neurodevelopment
Recipient
Kaiser Foundation Research Institute, Oakland, CA, United States
Award Amount
$636,731.00
Ceiling
$636,731.00
Awarded
June 26, 2026
Identifier
5R01ES037332-02
Research project studying gene-environment interactions affecting child neurodevelopment related to prenatal exposure to flame retardants, aiming to identify high-risk groups for autism and ADHD.
Description
Elucidating how genetic and environmental factors interact to improve understanding of autism and ADHD etiology and prevalence. The project uses genome-wide by environment interaction study and polygenic scores to study maternal and fetal genetics modifying the association between prenatal exposure to organophosphate ester flame retardants and child neurodevelopment. The goal is to identify high-risk groups and develop protective strategies for sensitive subgroups.