Award

National Institute of General Medical Sciences 5R16GM153598-03

Ontogeny of sex differences in amygdala and hypothalamus after neonatal trauma

Recipient

University of New England

Award Amount

$142,000.00

Ceiling

$142,000.00

Awarded

June 11, 2026

Identifier

5R16GM153598-03

Research project studying sex differences in brain and behavior effects of neonatal pain in rats, focusing on neuropeptide expression and neuronal activation to understand chronic pain and emotional disorder vulnerabilities.

Description

The project investigates sex differences in neonatal pain and stress effects on brain and behavior in rats, focusing on neuropeptide gene expression, neuronal activation, and brain-behavior correlations using advanced techniques like in situ hybridization and immunohistochemistry. It aims to understand mechanisms underlying sex-specific vulnerabilities to chronic pain and emotional disorders.

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