Award
National Institute of Mental Health 2R15MH127534-02
Differentiating fear generalization and extinction neuronal ensembles in prefrontal cortex
Recipient
Vassar College, Poughkeepsie, NY, United States
Award Amount
$556,875.00
Ceiling
$556,875.00
Awarded
July 28, 2026
Identifier
2R15MH127534-02
The award funds research at Vassar College to study neuronal processes underlying fear generalization and extinction in the prefrontal cortex, aiming to advance understanding and treatment of PTSD.
Description
This project investigates whether fear generalization and extinction are processed in mutually exclusive or overlapping neuronal substrates in the infralimbic cortex (IL) of the prefrontal cortex, with implications for understanding PTSD. The research uses transgenic mice, fiber photometry, and chemogenetics to study neuronal processes and aims to strengthen undergraduate biomedical research at Vassar College.