Award
NIH Reporter #5R44ES036902-03
Development of a Comprehensive Hen's Egg Model for Genotoxicity Testing
Recipient
National Institute of Environmental Health Sciences (NIEHS)
Award Amount
$645,357.00
Ceiling
$645,357.00
Awarded
August 14, 2026
Identifier
5R44ES036902-03
Award for developing a non-animal hen's egg model for genotoxicity testing to assess DNA damage potential of chemicals, funded by the National Institute of Environmental Health Sciences.
Description
The project involves developing, optimizing, and validating a hen’s egg model for genotoxicity testing to meet upcoming regulatory guidelines. It emphasizes non-animal, metabolically-active systems for genotoxic risk assessment using flow cytometry and high content imaging for automation, including assessment of genotoxic and cytotoxic biomarkers. The project is led by Erica Briggs with co-investigators Jeffrey C Bemis and Stephen D Dertinger.