# NIH Reporter #3R01NS129722-04S2

Serotonergic circuit mechanisms in postictal recovery and arousal

**Recipient:** University of Iowa

**Award Amount:** $37,729.00
**Ceiling:** $37,729.00

**Awarded:** September 11, 2026

**Identifier:** 3R01NS129722-04S2

Research project funded to study serotonergic circuit mechanisms involved in postictal recovery and arousal, with the goal of preventing seizure-related death in epilepsy models.

### Description

This project aims to understand how seizures impair CO2-arousal in mouse models of temporal lobe epilepsy and Dravet Syndrome, focusing on neuronal function in arousal-related brain regions, and testing interventions to prevent seizure-induced death.

[View original record](https://reporter.nih.gov/search/0C83gI3MXki4-tEhFD4UKQ/project-details/11617759)