Award
National Institute of Diabetes and Digestive and Kidney Diseases 1R03DK147560-01
Genetic dysregulation of mRNA translation in type 1 diabetes
Recipient
Yale University
Award Amount
$167,916.00
Ceiling
$167,916.00
Awarded
April 21, 2026
Identifier
1R03DK147560-01
Award for research on genetic dysregulation of mRNA translation in type 1 diabetes, aiming to uncover novel mechanisms and inform drug targets.
Description
This project focuses on the genetic regulation of RPS26 and its impact on mRNA translation in beta cells related to type 1 diabetes. The study involves genetic approaches, use of recombinant adeno-associated virus, and analysis of datasets from UK Biobank and DCCT/EDIC. The goal is to uncover novel mechanisms and inform drug targets for T1D treatment.