Award
National Institute of Allergy and Infectious Diseases 5R01AI164519-05
ACE and myeloid cell metabolism
Recipient
Cedars-Sinai Medical Center, Los Angeles, CA, United States
Award Amount
$560,426.00
Ceiling
$560,426.00
Awarded
January 31, 2026
Identifier
5R01AI164519-05
Research project funded by NIAID to study how increased ACE expression in myeloid cells enhances immune response by altering metabolism and ATP production.
Description
This project aims to increase myeloid cell function by increasing cell expression of angiotensin converting enzyme (ACE). The research shows that ACE expression in myeloid cells enhances immune responses by altering metabolism and increasing ATP production, which could be manipulated to improve human immune response.