Award

National Institute of Neurological Disorders and Stroke 1R61NS144491-01A1

Development of a multi-modal mouse model of cluster headache

Recipient

University of Texas HLTH SCI CTR HOUSTON, Houston, TX, United States

Award Amount

$392,223.00

Ceiling

$392,223.00

Awarded

June 19, 2026

Identifier

1R61NS144491-01A1

This award funds the development of a novel multi-modal mouse model to study cluster headache, addressing a critical need for disease-specific treatments by replicating key features of the disorder in an animal model.

Description

A project to create the first multi-modal animal model of cluster headache by combining a chemical trigger, brain/hypothalamus activation, and a mouse line lacking a genetic susceptibility gene. This model aims to provide insights into cluster headache pathophysiology and develop novel treatment strategies.

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