Award
NIH Reporter #5R01HL173346-03
Multi-Scale Systems Analysis of Metabolic and Mechanical Determinants of Reserve Cardiac Power Output
Recipient
University of Michigan at Ann Arbor
Award Amount
$290,652.00
Ceiling
$290,652.00
Awarded
August 13, 2026
Identifier
5R01HL173346-03
NIH awarded a grant to University of Michigan for a project using computational modeling to study cardiac power output and exercise intolerance in heart failure patients and healthy controls.
Description
This NIH grant supports research to develop and refine a multi-scale computational modeling framework for simulating whole-body exercise and cardiac energetics and mechanics in humans, aiming to understand physiological limitations to cardiac power and output reserve and exercise intolerance in heart failure.