Award
National Institute of Allergy and Infectious Diseases 1F31AI200262-01
Elucidating the antiviral mechanisms of OAS family innate immune sensors.
Recipient
University of Florida
Award Amount
$37,114.00
Ceiling
$37,114.00
Awarded
June 05, 2026
Identifier
1F31AI200262-01
The award supports research to define the molecular mechanisms and RNA substrates recognized by OAS family proteins in antiviral innate immune responses, potentially leading to new therapeutics against viral infections.
Description
This project aims to elucidate the molecular mechanisms of innate immune sensors, specifically focusing on the OAS family proteins and their role in antiviral responses. The research will utilize structural studies, CLIP-seq, and proximity labeling techniques to characterize the function and interactions of these proteins.