Award
NIH Reporter #PA-25-302
A NOVEL GEMM TO ELUCIDATE THE ROLE OF CHAF1A IN NEUROBLASTOMA DEVELOPMENT
Recipient
Baylor College of Medicine
Award Amount
$160,500.00
Ceiling
$160,500.00
Awarded
June 11, 2026
Identifier
PA-25-302
This NIH-funded project led by Dr. Eveline Barbieri at Baylor College of Medicine aims to develop a novel genetically-engineered mouse model to study the role of CHAF1A in neuroblastoma development, with a total award amount of $160,500 over two years.
Description
The project focuses on developing a genetically-engineered mouse model (GEMM) to study neuroblastoma. The research aims to elucidate the role of the CHAF1A gene in tumor initiation, progression, and immune microenvironment. The project employs advanced technologies such as ATAC-seq, lipidomics, and single-cell RNA sequencing.