Award
National Institute of Neurological Disorders and Stroke 3R01NS130130-04S1
Programmable Hydrogels for Optimized Human Oligodendrocyte Transplantation in Demyelinating Disease
Recipient
State University of New York at Buffalo
Award Amount
$64,913.00
Ceiling
$64,913.00
Awarded
July 16, 2026
Identifier
3R01NS130130-04S1
This award funds research to develop innovative hydrogels and animal models to improve human oligodendrocyte transplantation for treating demyelinating diseases like multiple sclerosis, addressing challenges in cell survival and differentiation to advance regenerative medicine.
Description
Design novel hydrogels to increase viability and enhance differentiation capacity of human oligodendrocytes upon transplantation to demyelinating brain; develop novel animal models of brain demyelination mimicking human diseases such as multiple sclerosis to test cell therapies; aims to enhance stem cell delivery for treatment of neurodegenerative diseases.