Award
NIH Reporter #5R01MH112355-11
Decoding Locus Coeruleus Neural Circuits and Signaling In Negative Affect
Recipient
Michael R. Bruchas
Award Amount
$518,012.00
Ceiling
$518,012.00
Awarded
May 08, 2026
Identifier
5R01MH112355-11
Research project awarded by the National Institute of Mental Health to study neural circuits and signaling in the locus coeruleus related to negative affect and stress using multidisciplinary methods.
Description
This project focuses on understanding neural circuits, receptors, and signaling pathways in the mammalian brain related to affective disorders and anxiety. It involves multidisciplinary approaches including molecular, cellular, neuropharmacological, imaging, and behavioral methods to study the locus coeruleus noradrenergic system and its role in stress and negative affect.