Award
National Heart, Lung, and Blood Institute 5R01HL131461-08
Polyunsaturated fatty acids as anti-arrhythmic agents.
Recipient
University of Miami School of Medicine, Coral Gables, FL, United States
Award Amount
$607,272.00
Ceiling
$607,272.00
Awarded
April 26, 2024
Identifier
5R01HL131461-08
The project focuses on testing compounds that activate IKs channels to restore normal cardiac action potential duration in Long QT Syndrome, using human cardiomyocytes, animal models, and heterologous systems to develop potential clinical therapies.
Description
This project aims to develop anti-arrhythmic drugs by testing compounds that activate IKs channels, restoring normal cardiac electrical activity, and preventing arrhythmias associated with Long QT Syndrome.