Award
National Institute on Aging 5K99AG090732-02
A calvarial stem cell mediating a new bone-brain axis in Alzheimer's disease
Recipient
Weill Medical College of Cornell University, New York, NY, United States
Award Amount
$134,325.00
Ceiling
$134,325.00
Awarded
May 14, 2026
Identifier
5K99AG090732-02
Research project investigating the role of calvarial skeletal stem cells in Alzheimer's disease progression and brain inflammation, with potential therapeutic implications.
Description
This project aims to determine how a newly identified skeletal stem cell in the calvarial bone influences Alzheimer's disease progression and establishes a new principle that skeletal cells in the skull regulate brain inflammation. The research will explore the presence of similar cells in humans and potential drug targeting strategies.