Award
National Heart, Lung, and Blood Institute 5R03HL174883-02
Non-genotoxic HSCT for ATM
Recipient
Emory University
Award Amount
$117,375.00
Ceiling
$117,375.00
Awarded
August 13, 2025
Identifier
5R03HL174883-02
Award for research on a non-genotoxic HSCT approach to treat Ataxia Telangiectasia, aiming to improve immune function and reduce cancer risk in mouse models.
Description
This project explores a novel, non-genotoxic hematopoietic stem cell transplantation (HSCT) approach for treating Ataxia Telangiectasia (A-T). The research aims to correct immune deficiencies, reduce lymphoma risk, and mitigate inflammation using immunotoxins in mouse models. The award is funded by the National Heart Lung and Blood Institute (NHLBI).