Award
NIH Reporter #5F31AR082689-03
The Epigenetic Regulation of Epidermal Stem Cells in Adult Skin Wound Healing
Recipient
Not specified
Award Amount
$23,747.00
Ceiling
$23,747.00
Awarded
March 20, 2026
Identifier
5F31AR082689-03
This award funds research on the epigenetic regulation of epidermal stem cells by PRC1 during adult skin wound healing, focusing on gene repression and cell migration mechanisms.
Description
The project investigates the role of PRC1, a chromatin regulator, in epidermal basal cell function during wound healing. It aims to elucidate mechanisms controlling the transcriptional switch in basal cells, focusing on PRC1's repression of epithelial fate genes and its influence on epithelial-mesenchymal plasticity (EMP) and cell migration.