Award
National Heart, Lung, and Blood Institute 5R01HL167700-03
Pathogenesis of Vascular Anomalies with GNAQ mutations
Recipient
Cincinnati Children's Hospital Medical Center
Award Amount
$581,713.00
Ceiling
$581,713.00
Awarded
March 23, 2026
Identifier
5R01HL167700-03
The award funds research to develop models for studying vascular anomalies caused by GNAQ mutations, with the goal of identifying therapeutic targets and treatments.
Description
This project aims to develop in vivo, in vitro, and Vessel-on-Chip models to identify cellular and molecular mechanisms involved in vascular disease related to GNAQ mutations. The research will investigate GNAQ's role in vascular lesion formation and expansion, aiming to identify therapeutic targets for vascular anomalies and related complications.