Award
National Heart, Lung, and Blood Institute 5R01HL179813-02
Cholesterol Regulation Through Retriever-Dependent LDL Receptor Recycling
Recipient
UT Southwestern Medical Center, Dallas, TX, United States
Award Amount
$686,687.00
Ceiling
$686,687.00
Awarded
March 09, 2026
Identifier
5R01HL179813-02
Research project funded by NHLBI to study the Retriever complex's role in LDL receptor recycling and cholesterol regulation to understand and manipulate cholesterol homeostasis.
Description
This project explores a key pathway controlling LDL receptor recycling in cells, focusing on the Retriever complex's role in cholesterol homeostasis and its physiological impact in animal models.