Award
National Cancer Institute PAR-25-135
From Atoms to Organoids: Understanding the Conformational Landscape and Regulation of Small GTPases
Recipient
University of Pittsburgh at Pittsburgh
Award Amount
$141,566.00
Ceiling
$141,566.00
Awarded
March 26, 2026
Identifier
PAR-25-135
Grant awarded for cancer-related research on small GTPases regulation and therapeutic target identification using advanced biological methods.
Description
A research project focused on the conformational landscape and regulation of small GTPases, specifically RhoA, in cancer. The project involves structural biology, in-cell NMR, organoid models, and aims to identify therapeutic targets in oncogenic RhoA.