Award
National Institute on Aging 5R01AG076018-05
Intersection of HSV-1 and microglial genetics in AD
Recipient
Columbia University Health Sciences, New York, NY, United States
Award Amount
$707,881.00
Ceiling
$707,881.00
Awarded
July 02, 2025
Identifier
5R01AG076018-05
Research project funded by the National Institute on Aging to study the interaction of HSV-1 infection and microglial genetics in Alzheimer's disease, focusing on immune response and genetic susceptibility.
Description
This project investigates the interaction between HSV-1 infection, immune response, and genetic susceptibility in Alzheimer’s disease (AD). It aims to identify how AD-related genetic variants influence microglia response to HSV-1, how microglia act as antigen-presenting cells, and how these interactions contribute to AD risk.