Award
NIH Reporter #4R01CA266641-04
Investigating the role of KAT6A in MLL-rearranged acute myeloid leukemia
Recipient
University of Pennsylvania
Award Amount
$733,489.00
Ceiling
$733,489.00
Awarded
September 15, 2025
Identifier
4R01CA266641-04
NIH grant awarded to University of Pennsylvania for research on KAT6A's role in MLL-rearranged acute myeloid leukemia, aiming to develop targeted therapies.
Description
This NIH grant project focuses on leukemia research, specifically targeting KAT6A and ENL proteins for therapeutic development in acute myeloid leukemia (AML). The project aims to elucidate mechanisms of KAT6A and ENL in AML and evaluate therapeutic potential of targeting KAT6A alone or in combination with other inhibitors in AML models and clinical samples.