Award

NIH Reporter #5K08DC022696-02

The Phex Pathway: Mechanisms Underlying a Meniere's Disease Subtype

Recipient

Massachusetts Eye and Ear Infirmary, Boston, MA, USA

Award Amount

$194,400.00

Ceiling

$194,400.00

Awarded

April 01, 2026

Identifier

5K08DC022696-02

This award supports research into a subtype of Meniere's disease linked to PHEX gene mutations, using human and mouse models to study inner ear maldevelopment and dysfunction.

Description

The project focuses on the mechanisms underlying a subtype of Meniere's disease related to PHEX gene mutations. It involves both human genetic studies and mouse models. The goal is to understand the developmental malformations of the inner ear and potential therapeutic interventions.

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