Award
NIH Reporter #5R01AI162786-05
TB Meningitis: Evaluating CSF Immunology to Discover Hidden Disease and Potential Immunomodulatory Therapies
Recipient
University of Minnesota, Minneapolis, MN, USA
Award Amount
$645,211.00
Ceiling
$645,211.00
Awarded
August 13, 2025
Identifier
5R01AI162786-05
Research project funded by NIAID to study immune responses in TB meningitis to improve diagnosis and treatment, focusing on HIV-associated cases and personalized therapies.
Description
This project seeks to characterize the immune system response in spinal fluid to TB meningitis. It aims to improve understanding of TB meningitis causes and immune responses, enabling better diagnosis and personalized immune therapies. The study focuses on HIV-associated TBM, exploring immune signatures, diagnostic sensitivity, and treatment responses through advanced immunologic profiling.