Award
National Eye Institute 5R01EY036466-03
Modulation of Corneal Endothelial Mitochondrial Activity and Dysfunction by Estrogen
Recipient
TRUSTEES OF INDIANA UNIVERSITY, Bloomington, IN, United States
Award Amount
$423,453.00
Ceiling
$423,453.00
Awarded
June 09, 2026
Identifier
5R01EY036466-03
Research project awarded by the National Eye Institute to study the effects of estrogen on corneal endothelial cells, focusing on mitochondrial activity and dysfunction, with implications for eye disease therapies.
Description
This project aims to determine if estrogen protects or damages corneal endothelial cells, with potential implications for therapies related to eye diseases such as FECD, glaucoma, and dry eye. The study involves mouse models, endothelial cell analysis, and assessment of mitochondrial activity and oxidative stress.