Award
National Heart, Lung, and Blood Institute 5R01HL180711-02
Role of hexokinase 3 in macrophage polarization and cardiac remodeling after myocardial infraction
Recipient
University of Arizona
Award Amount
$667,337.00
Ceiling
$667,337.00
Awarded
June 26, 2026
Identifier
5R01HL180711-02
Research grant to study the role of hexokinase 3 in macrophage polarization and cardiac remodeling after myocardial infarction, focusing on metabolic pathways and cardiac repair mechanisms.
Description
This project aims to assess HK3's role in macrophage polarization and its protective effects against cardiac damage post-myocardial infarction. The study involves generating HK3 knockout mice, analyzing macrophage metabolic pathways, and evaluating cardiac remodeling and function after ischemia/reperfusion injury.