Award
NIH Reporter #1R56AI203781-01
Improving the Innate Activity of Broadly Neutralizing Vectored Antibodies Against HIV
Recipient
Massachusetts General Hospital, Boston, MA, United States
Award Amount
$1,032,783.00
Ceiling
$1,032,783.00
Awarded
July 28, 2026
Identifier
1R56AI203781-01
Award for research to improve innate activity of broadly neutralizing vectored antibodies against HIV by modifying AAV vectors and defining Fc-receptor engagement rules to enhance HIV prevention.
Description
The project focuses on engineering the immune system via gene transfer to prevent HIV transmission. The research involves modifying AAV vectors to enhance immune responses. The project aims to define rules for Fc-receptor engagement to improve HIV prevention strategies. The project will use in vitro and in vivo models, including humanized mice.