Award
National Institute of Dental and Craniofacial Research 5R21DE033883-02
Exploring the function of novel arginine phosphorylation in streptococcal physiology
Recipient
University of Kansas Medical Center
Award Amount
$193,750.00
Ceiling
$193,750.00
Awarded
June 09, 2025
Identifier
5R21DE033883-02
The award supports research to understand the physiological role of arginine phosphorylation in Streptococcus mutans and to identify the kinase responsible for this modification, which may reveal new mechanisms of bacterial physiology and virulence.
Description
This project aims to unravel the role of arginine phosphorylation, a novel form of post-translational modification, in streptococci. It could identify a bacterial arginine kinase and provide new molecular insights into how arginine phosphorylation modulates the streptococcal proteome.