Award
NIH Reporter #5R00GM147355-04
A Functional Genomics Approach to Uncover the Mechanisms of Neutrophil Galvanotaxis
Recipient
University of Colorado
Award Amount
$249,000.00
Ceiling
$249,000.00
Awarded
August 27, 2026
Identifier
5R00GM147355-04
The award funds a research project at the University of Colorado to study the molecular mechanisms of neutrophil galvanotaxis using genome-wide CRISPRi screening, aiming to understand immune cell migration and its implications in inflammation and cancer.
Description
This project aims to develop technology for large-scale assays of galvanotaxis and perform a genome-wide CRISPRi knockdown screen to identify genes involved in neutrophil galvanotaxis, elucidating cellular mechanisms and pathways related to immune cell migration in response to bioelectric currents.