Award
NIH Reporter #1F31MH143445-01A1
The Impact of DNA Methylation on Microglial Innate Immune Memory Following Prenatal Immune Activation
Recipient
University of Oklahoma Health Sciences Center, Oklahoma City, OK
Award Amount
$47,914.00
Ceiling
$47,914.00
Awarded
August 06, 2026
Identifier
1F31MH143445-01A1
This award funds a study on the epigenetic effects of prenatal inflammation on microglial immune memory, exploring DNA methylation's role in neurodevelopmental disorders using a mouse model.
Description
Research project studying how prenatal inflammation epigenetically induces innate immune memory in microglia through DNA methylation, affecting immune reactivity and neurodevelopmental disorders.