# NIH Reporter #4R01AG079890-02

GPR39 as a Therapeutic Target in Aging-Related Vascular Cognitive Impairment and Dementia

**Recipient:** Oregon Health & Science University

**Award Amount:** $778,200.00
**Ceiling:** $778,200.00

**Awarded:** September 15, 2026

**Identifier:** 4R01AG079890-02

Award for research on GPR39 as a therapeutic target for aging-related vascular cognitive impairment and dementia, funded by the National Institute on Aging for fiscal year 2026.

### Description

The project involves developing a small molecule drug targeting GPR39 for aging-related dementia. The award is part of NIH PAR-22-031. The project is highly significant, translational, and innovative, including high-throughput screening, preclinical testing, and lead optimization. Funding is for fiscal year 2026.

[View original record](https://reporter.nih.gov/search/IgE1H2ioLUOz0qmA4MDg0Q/project-details/11463452)
