Award
National Institute of Allergy and Infectious Diseases 1K08AI199044-01
A Genetics Approach to Candida albicans Gastrointestinal Colonization Resistance
Recipient
University of California at Davis
Award Amount
$191,916.00
Ceiling
$191,916.00
Awarded
May 20, 2026
Identifier
1K08AI199044-01
Research project funded by NIAID to study Candida albicans colonization in the gastrointestinal tract and develop prevention strategies for invasive candidiasis, focusing on oxygen's role and drug impacts.
Description
The project aims to identify how Candida albicans colonizes the gastrointestinal tract and investigate new treatments to prevent invasive candidiasis. It explores the role of oxygen availability in colonization and dissemination, using mutants and models, and assesses the impact of drugs like 5-aminosalicyclic acid (5-ASA) and cyclophosphamide.