Award
Food and Drug Administration 5U01FD008429-02
Measuring Digital Clinical Endpoints in Huntington's Disease (MEND-HD)
Recipient
University of Rochester, Rochester, NY
Award Amount
$1,100,000.00
Ceiling
$1,100,000.00
Awarded
August 29, 2025
Identifier
5U01FD008429-02
This award funds a study to validate digital measures of motor impairments in early Huntington's disease using wearable sensors, supporting remote assessments for clinical trials.
Description
The project aims to establish the analytical validity and meaningfulness of digital measures of gait and chorea in early Huntington’s disease using wearable sensors. It involves a remote, cross-sectional study with individuals in early stages of Huntington's disease and control participants to demonstrate reliability, validity, and meaningfulness of digital measures as drug development tools and treatment response endpoints.