Award
NIH Reporter #1R21MH140210-01
Temporal interference methods for non-invasive deep brain stimulation
Recipient
TRUSTEES OF INDIANA UNIVERSITY
Award Amount
$420,519.00
Ceiling
$420,519.00
Awarded
May 07, 2025
Identifier
1R21MH140210-01
Award for research on non-invasive deep brain stimulation using temporal interference methods to study and potentially treat disorders involving deep brain regions.
Description
This project explores temporal interference (TI) electrical neurostimulation as a potential new technology to test causal hypotheses about deep brain function in human cognition, which may further provide a foundation for treating clinical disorders involving deeper brain regions such as addiction, OCD, schizophrenia, and Parkinson’s disease. The project involves combined TI and fMRI in human subjects to characterize the effect of TI on brain activity and functional connectivity, and applies TI to the dorsal anterior cingulate cortex to resolve debates about its causal role in cognition.