Award

NIH Reporter #11387764

Impact of developmental serotonin on prefrontal cortex parvalbumin interneuron excitability and cognitive behavior

Recipient

Columbia University Health Sciences

Award Amount

$33,057.00

Ceiling

$33,057.00

Awarded

July 31, 2026

Identifier

11387764

Research project funded by the National Institute of Mental Health studying the role of developmental serotonin in prefrontal cortex interneuron excitability and cognitive behavior, led by Amanda Anqueira at Columbia University Health Sciences.

Description

The project involves research on the impact of serotonin on prefrontal cortex interneurons and cognitive behavior. It aims to elucidate mechanisms contributing to cognitive behavior development and identify early risk factors of mental illness. The project involves electrophysiology, optogenetics, fiber photometry, and chemogenetics, focusing on developmental periods P14-P32 in mice. The project duration is from September 1, 2024, to February 28, 2027.

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